Neuropathy of the periphery

Peripheral neuropathy is characterised by weakness, numbness, and discomfort in the hands and feet as a result of nerve injury outside of the brain and spinal cord (peripheral nerves). It can also have an impact on other areas and activities of the body, such as digestion, urine, and circulation.

The peripheral nervous system relays information from the brain and spinal cord (central nervous system) to the rest of the body. Peripheral nerves also transmit sensory data to the central nervous system.

Traumatic injuries, infections, metabolic issues, hereditary reasons, and poisons can all induce peripheral neuropathy. Diabetes is one of the most common causes.

People suffering from peripheral neuropathy report their pain as stabbing, burning, or tingling. Symptoms often improve, especially if they are caused by a treatable ailment. Pregalin 50mg can help to alleviate the pain of peripheral neuropathy.

Because each nerve in your peripheral system serves a distinct purpose, symptoms vary depending on

Which Peripheral neuropathy are injured. Nerves are classed as follows:

Sensory nerves that receive sensations from the skin, such as temperature, discomfort, vibration, or touch

Motor nerves are the nerves that control muscle movement.

Blood pressure, sweat, heart rate, digestion, and bladder function are all controlled by autonomic nerves.

Among the signs and symptoms of peripheral neuropathy are:

  • Numbness, prickling, or tingling in your feet or hands that can travel up into your legs and arms
  • Sharp, jabbing, throbbing, or scorching discomfort
  • Touch sensitivity to the extreme
  • Pain during activities that should not cause pain, such as putting weight on your feet or putting them under a blanket.
  • Falling due to a lack of coordination
  • Muscle fatigue
  • Having the impression that you are wearing gloves or socks when you are not
  • Paralysis if the motor nerves are damaged

Signs and symptoms of autonomic nerve dysfunction may include:

  • Heat sensitivity
  • Excessive sweating or inability to sweat
  • Problems with the bowel, bladder, or digestion
  • Blood pressure drops, causing dizziness or lightheadedness

Peripheral neuropathy can affect one nerve (mononeuropathy), two or more nerves in distinct regions (multiple mononeuropathy), or several nerves (multiple polyneuropathy) (polyneuropathy). Mono neuropathy is exemplified by carpal tunnel syndrome. Polyneuropathy is the most common type of peripheral neuropathy.

When should you see a doctor?

If you detect unusual tingling, weakness, or pain in your hands or feet, seek medical attention straight away. Early diagnosis and therapy give you the best chance of treating your symptoms and preventing future nerve damage.


Peripheral neuropathy is a type of nerve injury caused by a variety of illnesses. The following medical disorders can produce peripheral neuropathy:

Autoimmune disorders Sjogren’s syndrome, lupus, rheumatoid arthritis, Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, and vasculitis are examples of these.

Diabetes. This is the most typical reason. More than half of diabetics will develop some form of neuropathy.

Infections. Certain viral or bacterial illnesses, such as Lyme disease, shingles, Epstein-Barr virus, hepatitis B and C, leprosy, diphtheria, and HIV, fall under this category.

Disorders that are inherited. Hereditary neuropathy disorders include Charcot-Marie-Tooth disease.

Neuropathies can also be caused by:

Alcoholism. Poor food choices made by alcoholics can result in vitamin shortages.

Poisoning exposure Industrial chemicals and heavy metals such as lead and mercury are examples of toxic compounds.

Medications. Certain drugs, particularly those used to treat cancer (chemotherapy), have the potential to cause peripheral neuropathy.

Nerve damage or compression Peripheral nerves can be severed or damaged as a result of events such as car accidents, falls, or sports injuries. Nerve pressure can be caused by wearing a cast, using crutches, or repeatedly performing a motion such as typing.

Deficiencies in vitamins B vitamins, particularly B-1, B-6, and B-12, as well as vitamin E and niacin, are essential for nerve health.

A number of instances have no identifiable cause (idiopathic)

  • Diabetes, particularly if your blood sugar levels are inadequately controlled.
  • Misuse of alcohol
  • Vitamin deficits, particularly B vitamin deficiencies
  • Lyme disease, shingles, Epstein-Barr virus, hepatitis B and C, and HIV are all examples of infections.
  • Rheumatoid arthritis and lupus are examples of autoimmune disorders in which your immune system assaults your own tissues.
  • Disorders of the kidneys, liver, or thyroid
  • Toxins exposure
  • Repetitive motion, such as that required for some jobs
  • Neuropathy runs in the family.
  • Complications

Peripheral neuropathy complications can include:

Skin damage and burns You may not notice temperature fluctuations or pain in numb areas of your body.

Infection. Without your knowledge, your feet and other sensitive parts might be harmed. Check these areas on a regular basis and treat small injuries immediately, especially if you have diabetes.

Falls. Lack of balance and falling can cause weakness and loss of sensation.


Control the underlying conditions. Taking Generic Lyrica is the best method to avoid peripheral neuropathy is to control any risk factors, such as diabetes, alcoholism, or rheumatoid arthritis.


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